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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
14.55
Human Site:
S24
Identified Species:
24.62
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S24
G
N
K
T
T
M
A
S
P
Q
L
M
P
L
V
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S24
G
N
K
T
T
M
A
S
P
Q
L
M
P
L
V
Rhesus Macaque
Macaca mulatta
P56490
532
60122
L27
Q
P
L
E
R
H
R
L
W
E
V
I
S
I
A
Dog
Lupus familis
XP_541769
536
61594
N73
G
N
K
T
T
I
A
N
P
K
L
M
P
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S24
G
N
R
T
A
M
A
S
P
Q
L
L
P
L
V
Rat
Rattus norvegicus
P31390
486
55674
S24
G
N
R
T
A
M
A
S
P
Q
L
L
P
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
L24
L
A
P
L
A
V
V
L
G
G
V
S
L
V
T
Chicken
Gallus gallus
P30372
466
51547
E25
E
S
P
Y
K
T
I
E
V
V
F
I
V
L
V
Frog
Xenopus laevis
P30544
484
54107
T30
E
I
P
G
K
Y
Q
T
M
E
M
I
F
I
A
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
H48
P
S
A
P
L
H
H
H
I
N
N
A
V
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
V73
D
S
C
G
E
L
R
V
V
D
H
N
Y
W
A
Honey Bee
Apis mellifera
XP_395477
546
60788
L79
P
V
L
P
P
F
E
L
W
Q
T
I
L
I
A
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
V39
T
E
E
P
A
A
I
V
W
R
H
P
L
L
A
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
L57
P
S
V
V
K
R
P
L
R
V
I
I
P
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
0
80
N.A.
80
80
N.A.
0
13.3
0
6.6
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
93.3
N.A.
20
26.6
33.3
13.3
N.A.
13.3
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
29
8
36
0
0
0
0
8
0
0
36
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
15
8
8
8
8
0
8
8
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% F
% Gly:
36
0
0
15
0
0
0
0
8
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
15
8
8
0
0
15
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
15
0
8
0
8
36
0
29
0
% I
% Lys:
0
0
22
0
22
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
15
8
8
8
0
29
0
0
36
15
22
58
0
% L
% Met:
0
0
0
0
0
29
0
0
8
0
8
22
0
0
0
% M
% Asn:
0
36
0
0
0
0
0
8
0
8
8
8
0
0
0
% N
% Pro:
22
8
22
22
8
0
8
0
36
0
0
8
43
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
36
0
0
0
0
0
% Q
% Arg:
0
0
15
0
8
8
15
0
8
8
0
0
0
0
0
% R
% Ser:
0
29
0
0
0
0
0
29
0
0
0
8
8
0
0
% S
% Thr:
8
0
0
36
22
8
0
8
0
0
8
0
0
0
8
% T
% Val:
0
8
8
8
0
8
8
15
15
15
15
0
15
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
22
0
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _